Cost savings in mass population screening for colorectal cancer resulting from the early detection and excision of adenomas
利用腺瘤发展数据和筛查试验中的患病率数据，预测了筛查中早期切除腺瘤所预防的癌症数量，并评估了节省的治疗成本，发现这些节省可抵消大规模筛查的部分总成本。
The widely-accepted hypothesis of a development sequence from colorectal adenoma to carcinoma is felt by clinicians to legitimate adenoma excision during routine colonoscopic investigation. Using published data on adenoma development, and adenoma prevalence data derived from the Nottingham colorectal cancer screening trial, the number of carcinomas prevented by early excision as a result of screening is predicted. The cost-effectiveness of early excision is then evaluated with reference to the expected treatment costs saved. These cost savings are found to represent a discount on the overall costs of mass population screening for colorectal cancer.