The Natural Selection of Infectious Disease Resistance and Its Effect on Contemporary Health
构建了一个衡量与病原体识别和清除相关基因系统遗传多样性的国家层面指标，发现该指标在流行病学转型前与健康结果正相关，转型后则无此关系。
This paper empirically tests the association between genetically determined resistance to infectious disease and cross-country health differences. A country-level measure of genetic diversity for the system of genes associated with the recognition and disposal of foreign pathogens is constructed. Genetic diversity within this system has been shown to reduce the virulence and prevalence of infectious diseases and is hypothesized to have been naturally selected from historical exposure to infectious pathogens. Base estimation shows a statistically strong, robust, and positive relationship between this constructed measure and country-level health outcomes in times prior to, but not after, the international epidemiological transition.