Evidence-based medicine and health economics: a case study of end stage renal disease
探讨如何将经济学评价框架与系统评价结合，以终末期肾病透析治疗为案例，发现简单经济学评价可行但存在结果可转移性等问题，为政策制定和未来研究提供参考。
This paper explores the potential for use of an economic evaluation framework alongside systematic reviews. Clinical issues in dialysis therapy for end stage renal disease are used as case studies. The effectiveness data required were obtained from a systematic review of randomized controlled trials. Resource use and cost data were obtained from three sources; the identified randomized controlled trials, a separate review of observational studies and primary data collection. The results of the case studies show that, although simple economic evaluations were possible, issues arose, such as how transferable results are between settings and how appropriate it is to focus on the average patient. The interface between economic evaluation and systematic reviews needs to be further developed in order to ensure that the best available evidence can be used to inform future policy and research.