Analyzing Bioterror Response Logistics: The Case of Anthrax
通过微分方程系统分析炭疽生物恐怖袭击的应对策略，推导出死亡人数与关键参数（如抗生素分发时间、传感器部署密度等）的近似公式，为应急决策提供依据。
To aid in understanding how best to respond to a bioterror anthrax attack, we analyze a system of differential equations that includes an atmospheric release model, a spatial array of biosensors, a dose-response model, a disease progression model, and a set of spatially distributed tandem queues for distributing antibiotics and providing hospital care. We derive approximate closed-form expressions for the number of deaths as a function of key parameters and management levers, including the size of the attack, the time at which the attack is detected via symptomatic patients, the number of days to distribute antibiotics, the efficacy (both for treatment and prevention) of antibiotics, the prophylactic antibiotic distribution strategy, the prioritization of the antibiotics queue, and the detection limit, deployment density, and delay time of biosensors.