Exposure to fluorocarbons during the filling and repair of air-conditioning systems in cars--a case report.
报告一名汽车厂工人因七年氟碳化合物暴露出现心电图异常、蛛网膜下腔出血和胸腺瘤，指出短期高浓度暴露可能比8小时平均浓度更值得关注。
A worker exposed to fluorocarbons in an automobile plant for seven years experienced shortness of breath (in 1977) and was referred to the hospital. The clinical examination revealed electrocardiographic abnormalities. He recovered quickly and returned to work. During the following year (1978) he suffered subarachnoid bleeding with hemiparesis, and four years later he had an operation for a thymoma. Hygienic measurements in 1980-1981 showed large variations in the fluorocarbon concentrations in the plant, the average 8-h concentrations being below the occupational exposure limit of 500 ppm but several short-time measurements reaching levels of over 750 ppm. It was suggested that, persons with heart disease do not necessarily have to be removed from work with fluorocarbons without careful review of the exposure but that the evaluation of the exposure should not only be based on time-weighted average concentrations, but also on values for brief periods, in that such concentrations can often be decreased by simple and cheap measures.