The Epidemiology of Childhood Leukaemia
本文综述了儿童白血病的类型、病因及发病率变化，指出多数病因未知，少数与遗传或出生后化疗有关，更多与电离辐射暴露相关，并讨论了年龄、地域、种族等分布特征。
Leukaemias are of several types, the proportion attributable to each varying with age. The causes of most childhood leukaemias are unknown. A few are associated with genetic abnormalities and a few to chemotherapy given after birth. Many more are due to exposure to ionizing radiation with possibly 8 % attributable to exposure to natural radiation in utero. Clues to aetiology may be obtained from the age distribution of the disease and the variation in incidence with place, ethnicity, socioeconomic conditions and time; but much of the variation is likely to be a nosological artefact. The existence of clusters in space and time, which would point to the importance of environmental factors, has long been suspected but is unproved.