北欧四国职业性极低频磁场或电击暴露与癌症发病率的关系

0400 Occupational exposure to extremely low frequency magnetic fields or electric shocks and cancer incidence in four Nordic countries

Occupational and Environmental Medicine · 2014
被引 1
ABS 3

中文导读

基于北欧四国大型职业队列,研究职业性极低频磁场或电击暴露与脑癌、血液淋巴系统癌症及乳腺癌发病率的关系,未发现显著关联。

Abstract

<h3>Objectives</h3> To evaluate the association between occupational exposure to extremely low frequency magnetic fields (ELF-MF) or electric shocks and brain cancer, haemopoietic and lymphatic malignancies, and breast cancer incidence in the Nordic Occupational Cancer cohort. <h3>Method</h3> The cohort was set up by linking occupational information from national censuses held in 1960, 1970, 1980–1, and/or 1990 to national cancer registry data in Finland, Iceland, Norway, and Sweden. All subjects aged 30–64 years who participated in a census were followed-up for cancer incidence until 2003–2005. Occupational exposure to ELF-MF or electric shocks (low, medium, high) was assigned to each subject based on census reported jobs using job-exposure matrices. For each case, five controls were randomly selected by matching for country, age, and sex. Conditional logistic regression models were performed adjusting for social class and occupational exposure to solvents. <h3>Results</h3> A total of 68 770 brain cancer cases, 65 609 non-hodgkin lymphoma cases, 83 088 leukaemia cases, 33 791 multiple myeloma cases, 1827 male breast cancer cases, and 297,283 female breast cancer cases were included. Thirty-five percent of the total population was ever exposed to medium levels of ELF-MF and 7% to high levels, whereas 19% was ever exposed to a medium risk of electric shocks and 13% to a high risk. No associations were found between occupational exposure to ELF-MF or electric shocks and any of the cancer outcomes. <h3>Conclusions</h3> In this very large census cohort we found no evidence of increased risk of several cancers in relation with occupational exposure to ELF-MF or electric shocks.

职业医学癌症流行病学环境健康电磁场暴露