0242 Impact of occupation on blood lead levels in pregnant women
在墨西哥杜兰戈的299名孕妇中，研究发现从事有铅暴露风险职业的女性血铅≥5 µg/dL的比例显著更高，提示孕期需加强职业暴露监测。
<h3>Objectives</h3> To examine the relationship between occupation and blood lead levels in pregnant women of Durango, Mexico. <h3>Method</h3> A cross sectional study was conducted with 299 pregnant women. Information on occupation, risk factors and sociodemographic data was collected by means of a structured questionnaire. Blood lead concentration was tested by graphite furnace spectrometry. Women were divided into three groups according to occupation: working in places with potential source of lead exposure (exposed group), working in places without lead exposure (control group I), and non-working women (control group II). The X<sup>2</sup> test was used to assess statistical differences between the groups, and one way ANOVA was applied for comparisons. Logistic regression was performed using blood lead < 5 µg/dL or ≥ 5 µg/dL as dependent variable, and ajdusted for jurisdiction, income, gestational age, and abortions. <h3>Results</h3> Only 24(8%) women worked in places with potential source of lead exposure, 47(15.7%) worked in other places, and 228(76.3%) did not have a remunerated job. Mean blood lead concentration in the study sample was 2.79 µg/dL. However, blood lead ≥ 5 µg/dL accounted for 25% of exposed women, 2.1% of control group I, and 6% of control group II (X<sup>2</sup> = 13.04; p .001). Mean blood lead level was 4.24 µg/dL in the exposed group, 2.31 µg/dL in the control group I, and 2.74 µg/dL in the control group II; those differences were statistically significant (0.001). Logistic regression confirmed that blood lead ≥ 5 µg/dL is associated with occupational exposure (p = 0.036). <h3>Conclusions</h3> Our findings suggest that surveillance for occupational exposure to prevent health damages during pregnancy is needed.