Biological half-time of cadmium in the blood of workers after cessation of exposure.
研究了5名曾接触镉的工人在停止接触后10至13年间血液镉浓度的下降规律，发现双室模型拟合最佳，快相半衰期75-128天，慢相半衰期7.4-16.0年，证实镉在体内有极长的生物半衰期。
The biological half-time of cadmium in the blood of previously exposed workers was estimated after the cessation of exposure. Five men were followed for a period of 10 to 13 years. One-compartment and two-compartment exponential elimination models were used to describe the decrease in blood cadmium levels over time. The best fit to the observed data was obtained with a two-compartment model. The half-times estimated from this model ranged from 75 to 128 d for the fast component and from 7.4 to 16.0 years for the slow component. The results confirm that there is a very long whole-body biological half-time for cadmium, and the estimated half-times are similar to those obtained with different methods.