Car painters` exposure to a mixture of organic solvents. Serum activities of liver enzymes.
研究了102名汽车油漆工接触有机溶剂混合物(浓度约为ACGIH阈限值一半)后血清肝酶活性,发现与对照组无显著差异,且受影响亚组酶活性也未升高。
The serum activities of liver enzymes of car painters (N = 102) exposed to a mixture of solvents [toluene, xylene, and other constituents; about half the threshold limit value recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) in 1981] were compared with those of age-matched referents (N = 102). The activities of aspartate aminotransferase, alanine aminotransferase, ornithine carbamoyl transferase, and gamma glutamyl transferase did not differ between the exposed and the nonexposed groups. Simultaneous neurophysiological and ophthalmological examinations of the same car painters had distinguished subgroups of "solvent-affected" and "non-affected" car painters. The enzyme activities were not higher in the "affected" subgroups than in the "nonaffected" ones. The results suggest that car painters' exposure to organic solvents (at the overall level of half the threshold limit value of the ACGIH) does not increase liver enzyme activities in routine tests.