Allergic airway disease caused by methyl tetrahydrophthalic anhydride in epoxy resin.
研究了一名工人因接触环氧树脂固化剂甲基四氢苯酐而出现工作相关鼻炎和哮喘,证实该病由IgE介导的过敏反应引起。
Work-associated rhinitis and asthma occurred in a subject exposed to methyl tetrahydrophthalic anhydride (MTHPA) used as a curing agent in an epoxy resin system. He displayed bronchial hyperreactivity in provocation with methacholine, as well as skin prick test positivity and specific immunoglobulin E (IgE) serum antibodies, against a conjugate of MTHPA and human serum albumin. Thus, it seems likely that the disease was caused by an IgE-mediated allergy.