60 Cancer morbidity of lead exposed workers in korea
研究比较了韩国铅暴露工人与普通人群的癌症发病率，发现铅铬酸盐工人胃癌风险升高，且铅暴露与肾癌、膀胱癌和女性肺癌存在剂量反应关系。
<h3>Objectives </h3> To compare cancer patterns in lead exposed workers with the Korean general population, and to explore the relationship between cancer and lead exposure in an occupational setting. <h3>Methods</h3> Using from the Korean annual medical surveillance for exposure to lead, a cohort comprising 75,184 lead exposed workers working between January 1<sup>st</sup>, 2000 and December 31<sup>st</sup>, 2004 was compiled. This cohort was merged with the Korea National Central Cancer Registry (KNCCR) in order to evaluate the cancer morbidity for these workers between 2000 and 2008. <h3>Results</h3> Therewere 793 cases cancer and, the incidence of stomach cancer (SIR 1.17, 95% CI = 1.01–1.36) was found to be elevated in lead chromate workers. Excesses were observed for kidney (2.15.1.19–3.88) and bladder cancers (2.29.1.149–4.58) in lead exposed workers ≥20 years of job duration, kidney cancer (2.25.1.21–4.18)in workers with ≥10 ug/dl of blood lead level and lung cancer in female workers with ≥10 ug/dl blood lead level. <h3>Conclusions </h3> Our study showed excess of lung cancer in female workers, stomach cancer in lead chromate exposed workers and a possible dose-response relationship between d kidney cancers and lead exposure.