Predictors of blood lead concentrations in the lead-free gasoline era
研究了丹麦参考人群中血铅浓度与工作、环境及生活方式的关系,发现年龄、性别、更年期状态和饮酒等传统预测因素在低铅暴露下仍有效,且维生素矿物质补充与血铅呈负相关。
OBJECTIVES: Blood lead concentrations in a Danish reference population were related to information from an extensive questionnaire on work, environment, and life-style. METHODS: Data were gathered for 209 persons by means of a questionnaire and blood lead analyses. RESULTS: The mean concentration of lead in blood was 0.167 micromol/l (ie, significantly lower than in previous studies). This finding is in accordance with the fact that less than 10% of the gasoline used in Denmark contains lead additives (up to 0.15 g/l). An important finding was that the well-documented predictors for lead in blood at higher concentration levels, such as age, gender, menopausal status, and intake of alcohol, are still valid in a low-level exposure situation. In addition, a strong and negative correlation was found between blood lead concentrations and dietary supplementation with vitamins and minerals. CONCLUSIONS: The present data indicate that lead exposure may still constitute a health risk in a small proportion of adult men and postmenopausal women.