低水平(非热)100 MHz射频辐射对大鼠无胚胎毒性效应

Absence of embryotoxic effects from low-level (nonthermal) exposure of rats to 100 MHz radiofrequency radiation.

Scandinavian Journal of Work Environment & Health · 1983
被引 18
ABS 3

中文导读

该研究让怀孕大鼠在妊娠第6-11天每天暴露于100 MHz射频辐射6小时40分钟,总暴露40小时,发现其未导致胚胎毒性或致畸效应,对评估射频辐射安全标准有参考价值。

Abstract

Pregnant Sprague-Dawley rats were exposed to radio-frequency radiation at a frequency of 100 MHz and a power density of 25 mW/cm2 for 6 h 40 min daily on gestation days 6--11. The total exposure time was 40 h. The exposure resulted in a specific absorption rate of 0.4 W/kg. This value corresponds to the maximum permissible level for specific absorption rate in the 1982 American National Standards Institute (ANSI) standard for radiofrequency/microwave exposure. The exposure produced no increase in maternal colonic temperature. Irradiated rats did not differ from sham-irradiated rats with respect to the number of implantations per litter, percentage of implantations dead or resorbed, percentage of fetuses malformed. fetal weight, fetal crown-rump length, or fetal sex ratio. The irradiated fetuses had fewer minor skeletal variations than the controls. These results suggest that radiofrequency/microwave radiation is not teratogenic or embryotoxic for rats at the maximum permissible exposure level of the 1982 ANSI standard.

毒理学生殖医学辐射生物学动物实验