Occupational noise exposure and course of pregnancy.
基于芬兰先天性畸形登记处的病例对照研究，分析了职业噪声暴露与不良妊娠结局的关系，发现噪声与轮班工作共同作用时，先兆流产和妊娠高血压风险增加，且妊娠期缩短。
The study examined the possible relation of occupational noise exposure to adverse pregnancy outcomes. The experience of 1,190 reference mothers from a case-referent study based on the Finnish Register of Congenital Malformations was scrutinized. Exposure to noise was blindly assessed from a description of the mother's workday by two industrial hygienists. Women with an estimated level of noise of around 80 dB LAeq(8 h) or higher were considered exposed. Threatened abortion was not associated with noise exposure alone, but, when it was combined with shift work, the adjusted risk was over twofold. The adjusted risk of pregnancy-induced hypertension was twice as high among the mothers exposed to noise in shift work, and the duration of their pregnancy was shorter. The analyses produced indications of a relation between noise and growth retardation which was not connected with shift work. There were significantly ascending trends in the proportions of these outcomes according to increasing exposure intensity.