AGRICOH, a newly formed consortium of agricultural cohorts
AGRICOH是一个由22个农业队列组成的国际联盟，覆盖9个国家，旨在通过数据整合研究农业中多种暴露（如农药、柴油废气）与健康结局（如癌症、呼吸系统疾病）的关联，尤其关注单个队列难以研究的罕见暴露或疾病。
<h3>Objectives</h3> We recently formed AGRICOH, a consortium of agricultural cohort studies, offering the opportunity to investigate potential health effects of a wide range of occupational and environmental exposures coexisting in agriculture. <h3>Methods and results</h3> AGRICOH is a consortium of 22 agricultural cohort studies initiated by US National Cancer Institute (NCI) and coordinated by International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries in 5 continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate associations between a wide range of agricultural exposures (eg, pesticides, diesel exhausts, organic dust, inorganic dust, mycotoxins, endotoxins, viruses) and a wide range of health outcomes (eg, cancer, respiratory, neurologic, auto-immune diseases, as well as reproductive and allergic disorders and injuries), with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (eg, use of infrequently applied pesticides) or relatively rare outcomes (eg, certain types of cancer, neurologic and auto-immune diseases). To facilitate future projects need for data harmonisation is required and underway. Characteristics of cohorts integrating AGRICOH, the wide range of exposures data available, data harmonisation challenges and research concepts will be illustrated. <h3>Conclusions</h3> AGRICOH represents a great resource for conducting validation of exposure assessment and etiologic studies in association with a wide array of exposures unique to, or showing the highest likelihood of exposure, in the agricultural setting.