Effect of Local Vibration on the Brain Monoamines of Rats
实验研究局部振动对大鼠脑内去甲肾上腺素、多巴胺和血清素水平的影响，并与全身振动比较，发现局部振动影响较小。
The experimental study investigated the effect of local vibration on brain monoamines, and the effect was compared with that of whole-body vibration. The hind legs of rats were exposed to local vibration with frequencies of 20 and 120 Hz under constant acceleration of 50 m/s^2 for 240 min. The rats were decapitated immediately thereafter. The levels of norepinephrine (NE), dopamine (DA), and serotonin (5-HT) in the whole brain or its parts were detected by fluorometric methods. In the whole brain, the NE level showed a tendency to decrease at 120 Hz. The levels of DA and 5-HT showed no changes at either frequency. NE showed a significant decrease at 120 Hz in the hypothalamus and the hippocampus. 5-HT showed significant increases in the hypothalamus at both 20 and 120 Hz. The amines in the whole brain were not significantly affected by local vibration (20 Hz, 50 m/s^2), but were by whole-body vibration (20 Hz, 50 m/s^2). The NE level was significantly decreased by whole-body vibration (20 Hz, 50 m/s^2) and showed a tendency to decrease due to exposure to local vibration (120 Hz, 50 m/s^2). 5-HT was remarkably elevated by whole-body vibration, but less elevated by local vibration. Thus the effects induced in brain monoamines by local vibration are considerably less than those induced by whole-body vibration.