Overview of MEG
介绍了脑磁图(MEG)技术,它通过记录头外神经磁场研究人脑电活动,具有毫秒级时间分辨率和毫米级空间定位精度,并举例说明了其在正常与阅读障碍者口语处理研究中的应用。
Magnetoencephalography (MEG) is a method to study electrical activity in the human brain by recording the neuromagnetic field outside the head. MEG, like electroencephalography (EEG), provides an excellent, millisecond-scale time resolution, and allows the estimation of the spatial distribution of the underlying activity, in favorable cases with a localization accuracy of a few millimeters. To detect the weak neuromagnetic signals, superconducting sensors, magnetically shielded rooms, and advanced signal processing techniques are used. The analysis and interpretation of MEG data typically involves comparisons between subject groups and experimental conditions using various spatial, temporal, and spectral measures of cortical activity and connectivity. The application of MEG to cognitive neuroscience studies is illustrated with studies of spoken language processing in subjects with normal and impaired reading ability. The mapping of spatiotemporal patterns of activity within networks of cortical areas can provide useful information about the functional architecture of the brain related to sensory and cognitive processing, including language, memory, attention, and perception.