Testing for family influences on obesity: The role of genetic nurture
利用Add Health的遗传数据,检验兄弟姐妹间体重指数(BMI)的正相关性是否由基因养育(即兄弟姐妹基因对个体体重的影响)造成,结果未发现可信证据支持这一机制。
A large literature has documented strong positive correlations among siblings in health, including body mass index (BMI) and obesity. This paper tests whether that is explained by a specific type of peer effect in obesity: genetic nurture. Specifically, we test whether an individual's weight is affected by the genes of their sibling, controlling for the individual's own genes. Using genetic data in Add Health, we find no credible evidence that an individual's BMI is affected by the polygenic risk score for BMI of their full sibling when controlling for the individual's own polygenic risk score for BMI. Thus, we find no evidence that the positive correlations in BMI between siblings are attributable to genetic nurture within families.