The Scourge of Asian Flu: In utero Exposure to Pandemic Influenza and the Development of a Cohort of British Children
研究了1957年亚洲流感大流行期间子宫内暴露对英国儿童身体和认知发展的影响,发现身体发育受损仅发生在特定母亲健康特征的子群体中,而认知发展的负面影响则普遍存在。
This paper examines the impact of in utero exposure to the Asian influenza pandemic of 1957 upon childhood development. Outcome data are provided by the National Child Development Study (NCDS), a panel study where all members were potentially exposed in the womb. Epidemic effects are identified using geographic variation in a surrogate measure of the epidemic. Results point to multiple channels linking fetal health shocks to childhood outcomes: physical development is impeded, but only when mothers had certain health characteristics; by contrast, the negative effects on cognitive development appear general across the cohort.