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随机截断数据的半参数模型

A Semiparametric Model for Randomly Truncated Data

Journal of the American Statistical Association · 1989
被引 28
ABS 4

中文导读

研究了随机截断数据在半参数模型下的最大似然估计,发现截断机制的参数信息会影响估计,不同于删失数据的情况,并给出了估计的大样本性质。

Abstract

Abstract For randomly censored data, it is known that the maximum likelihood estimate (MLE) of the survival curve is not affected by parametric assumption on the censoring variable. The Kaplan-Meier (1958) estimate is the MLE for both nonparametric and semiparametric models. For randomly truncated data, the truncation product-limit estimate is the MLE for nonparametric models. This is not the case if the truncation mechanism is parameterized, however. Specifically, let X be a generic random variable and T be the truncation variable. If the distribution of T is parameterized and the distribution of X is left unspecified, it can be shown that the truncation product-limit estimate is not the MLE for this semiparametric model, even though it is for the fully nonparametric model. In this article the MLE is characterized for the semiparametric model, and the large-sample properties of the estimate are established. The results show that, unlike censoring, the parametric information from the truncation mechanism influences the estimation procedures. Several examples in biostatistics, in which the truncation distribution can be interpreted as the infection distribution or the birth distribution, are considered.

生物统计学生存分析半参数模型截断数据