基于倾向性评分的有效且稳健的人群推断方法:利用流行病学队列

Efficient and robust propensity‐score‐based methods for population inference using epidemiologic cohorts

International Statistical Review · 2021
被引 9
ABS 3

中文导读

针对流行病学队列样本不具代表性的问题,提出一种放宽交换性假设的倾向性评分核加权方法,通过缩放调查权重提高估计效率,在模拟和实例中均表现更优。

Abstract

Summary Most epidemiologic cohorts are composed of volunteers who do not represent the general population. To improve population inference from cohorts, propensity‐score (PS)‐based matching methods, such as PS‐based kernel weighting (KW) method, utilise probability survey samples as external references to develop PSs for membership in the cohort versus survey. We identify a strong exchangeability assumption (SEA) that underlies existing PS‐based matching methods whose failure invalidates inferences, even if the propensity model is correctly specified. Herein, we develop a framework of propensity estimation and relax the SEA to a weak exchangeability assumption (WEA) for matching methods. To recover efficiency, we propose a scaled KW (KW.S) matching method by scaling survey weights in propensity estimation. We prove consistency of KW.S estimators of means/prevalences under WEA and provide consistent finite population variance estimators. In simulations, the KW.S estimators had smallest mean squared error (MSE). Our data example showed the KW estimates requiring the SEA had large bias, whereas the proposed KW.S estimates had the smallest MSE.

流行病学因果推断统计方法倾向性评分匹配人群推断