带删失生存数据的稳健推断

Robust inference with censored survival data

Scandinavian Journal of Statistics · 2022
被引 1
ABS 3

中文导读

研究了带删失生存数据下的一类有界影响函数M估计量,给出了渐近性质并定义了稳健的Wald、得分和似然比检验,通过模拟和头颈癌数据验证了性能。

Abstract

Abstract Randomly censored survival data appear in a wide variety of applications in which the time until the occurrence of a certain event is not completely observable. In this paper, we assume that the statistician observes a possibly censored survival time along with a censoring indicator. In this setting, we study a class of M‐estimators with a bounded influence function, in the spirit of the infinitesimal approach to robustness. We outline the main asymptotic properties of the robust M‐estimators and characterize the optimal B‐robust estimator according to two possible measures of sensitivity. Building on these results, we define robust testing procedures which are natural counterparts to the classical Wald, score, and likelihood ratio tests. The empirical performance of our robust estimators and tests is assessed in two extensive simulation studies. An application to data from a well‐known medical study on head and neck cancer is also presented.

生存分析稳健统计计量经济学生物统计假设检验