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控制多重检验中错误发现超额的广义增强方法

Generalized Augmentation to Control the False Discovery Exceedance in Multiple Testing

Scandinavian Journal of Statistics · 2009
被引 1
ABS 3

中文导读

提出一种新的多重检验程序GAUGE,能控制错误发现超额并具有竞争力,可推广至其他错误度量,适用于依赖数据,并在前列腺癌和结肠癌数据上验证。

Abstract

Abstract. A new multiple testing procedure, the generalized augmentation procedure (GAUGE), is introduced. The procedure is shown to control the false discovery exceedance and to be competitive in terms of power. It is also shown how to apply the idea of GAUGE to achieve control of other error measures. Extensions to dependence are discussed, together with a modification valid under arbitrary dependence. We present an application to an original study on prostate cancer and on a benchmark data set on colon cancer.

多重检验统计假设检验错误发现率生物信息学癌症研究