Exact Confidence Intervals Following a Group Sequential Trial: A Comparison of Methods
本文比较了组序贯临床试验结束后构建参数置信区间的几种方法,并与已有文献方法对比,指出有趣差异,对统计学家和临床研究人员有用。
With interest in designing group sequential clinical trials increasing, methodology for analysing the data arising in such trials is needed. We discuss several approaches to constructing confidence intervals for the parameter of interest in a group sequential trial after the trial has ended. We compare these methods to one already in the literature and point out interesting differences.