Nonparametric Bayesian Bioassay with Prior Constraints on the Shape of the Potency Curve
研究了在生物测定问题中,当先验约束效力曲线形状(如凸、凹或S形)时,如何实现非参数贝叶斯分析,并详细说明了基于抽样的后验特征计算方法。
We consider the problem of implementing nonparametric Bayesian analysis of bioassay problems when the prior constrains the form of the potency curve (for example, to be convex, concave or ogive). Sampling based approaches to calculating posterior features of interest are detailed and illustrated. Extensions to prior constraints on hazard rates are outlined.