Improvements in activities of daily living among patients with brain tumors are associated with age, baseline physical function, duration of rehabilitation, and tumor recurrence but not type
这项回顾性研究分析了358名脑肿瘤患者的康复数据，发现年龄较大、肿瘤复发、入院前功能状态较差和基线功能较高会降低康复效果，而每日治疗时长越长则效果越好，但肿瘤类型对改善程度没有影响。
Genetic testing has improved the accuracy of diagnosis of brain tumors, and treatment is now tailored to the type of brain tumor. In contrast, the factors that influence the improvement in independence in activities of daily living (ADLs) following rehabilitation have not been clarified, particularly the role of tumor type. In this retrospective cohort study of 358 participants, we analyzed changes in the Functional Independence Measure (FIM) from pre-rehabilitation to post-rehabilitation provided in an acute care hospital. Multiple regression was used to determine whether FIM gain is associated with age, gender, preadmission Karnofsky Performance Status (KPS), number of rehabilitation days, average duration of daily therapy (min/day), and tumor recurrence and type (WHO grade 1, 2, 3, and 4 gliomas; primary central nervous system lymphomas; and metastatic brain tumors). The results showed that older age ( β -0.183), tumor recurrence ( β -0.137), preadmission KPS < 80 ( β -0.180), and higher baseline total FIM score ( β -0.470) were associated with lower FIM gain whereas the average duration of daily therapy ( β 0.153) was associated with higher FIM gain. Brain tumor type was not associated with FIM gain. Improved independence in ADLs is more influenced by demographic, functional status, and treatment factors than differences in brain tumor type.