企业强制性研发信息披露的时机、修改和基调:竞争的作用

Timing, modifications, and tenor of firms' mandatory R&D disclosures: The role of competition

RESEARCH POLICY · 2024
被引 6
人大 AFT50ABS 4*

中文导读

研究竞争压力如何影响制药企业在ClinicalTrials.gov上履行强制性临床试验信息披露的时机、目标修改和正面基调使用,发现竞争加剧促使企业更快披露但更多修改目标并关联正面论文。

Abstract

Regulatory requirements for disclosure are often designed to advance transparency and public welfare. Yet, firms may approach these mandates with caution. In this study, we investigate the role of competitive pressures on firms' discretion in fulfilling mandatory R&D disclosures. We focus on pharmaceutical firms required to publish their clinical trial results on ClinicalTrials.gov and examine three key elements of disclosure: the timing of disclosure, modifications to pre-established research objectives, and the use of positively toned scientific publications. These disclosure elements are crucial because they can potentially undermine the regulatory goals of enhancing transparency and public welfare. Our findings indicate that, under intense competition, firms disclose their R&D results more promptly. However, they make more extensive changes to their stated research objectives and are more likely to link positively toned scientific publications to their disclosures. We discuss the implications of our findings for the literature on R&D disclosures and questionable reporting, as well as for regulators and policymakers enforcing disclosure mandates. • Regulatory disclosure mandates aim for transparency, but firms proceed cautiously. • We investigate how competition affects mandatory R&D disclosures in clinical trials. • A standard deviation increase in competition shortens disclosure time by 47 days. • Competition leads to significant edits in research objectives post-study completion. • Competition prompts firms to support disclosures with positively toned papers.

企业信息披露竞争制药行业研发管理