从观察性研究中同时估计多个处理效应

Simultaneous Estimation of Multiple Treatment Effects from Observational Studies

Journal of Computational and Graphical Statistics · 2025
被引 0
ABS 3

中文导读

提出一种新的因果推断方法,利用多个处理间的稀疏结构,自动筛选有因果效应的处理并给出稀疏估计,在模拟和GWAS数据上表现优于现有方法。

Abstract

Unmeasured confounding presents a significant challenge in causal inference from observational studies. Classical approaches often rely on collecting proxy variables, such as instrumental variables. However, in applications where the effects of multiple treatments are of simultaneous interest, finding a sufficient number of proxy variables for consistent estimation of treatment effects can be challenging. Various methods in the literature exploit the structure of multiple treatments to address unmeasured confounding. In this paper, we introduce a novel approach to causal inference with multiple treatments, assuming sparsity in the causal effects. Our procedure autonomously selects treatments with non-zero causal effects, thereby providing a sparse causal estimation. Comprehensive evaluations using both simulated and Genome-Wide Association Study (GWAS) datasets demonstrate the effectiveness and robustness of our method compared to alternative approaches.

因果推断观察性研究工具变量高维统计基因组关联研究