A Bayesian zero-inflated spatially varying coefficients model for overdispersed binomial data
针对孕期心血管代谢风险因素（CRFs）的过分散和零膨胀二项计数数据，提出了一个零膨胀贝塔二项空间变系数模型，并用于分析南卡罗来纳州非西班牙裔白人和黑人女性在COVID-19疫情期间的种族差异时空趋势。
Cardiometabolic risk factors (CRFs) during pregnancy are early indicators of maternal diseases, such as stroke and type 2 diabetes. The total number of CRFs typically takes the form of binomial counts that exhibit overdispersion and zero inflation due to correlations among the underlying CRFs. Motivated by an examination of spatiotemporal trends in five CRFs among pregnant women in the U.S. state of South Carolina during the COVID-19 pandemic, we developed a zero-inflated beta-binomial model within a spatiotemporal framework. This model combines a point mass at zero to account for zero inflation and a beta-binomial distribution to model the remaining CRF counts. Given the notable racial disparities in CRFs during pregnancy that vary across the state over time, we incorporate a spatially varying coefficient model to explore the complex relationships between CRFs and geographic and temporal disparities among non-Hispanic White and non-Hispanic Black women. For posterior inference, we developed an efficient hybrid Markov Chain Monte Carlo algorithm that relies on easily sampled Gibbs and Metropolis-Hastings steps. Our analysis of CRFs in South Carolina reveals that certain counties, such as Chesterfield and Clarendon, exhibit gaps in racial health disparities, making them prime candidates for community-level interventions aimed at reducing these disparities.