Understanding the demographics of the opioid overdose death crisis
分析了美国阿片类药物危机中不同人口群体的过量死亡趋势，发现调整协变量后许多差异加剧，并揭示了奥施康定上市对性别和教育程度群体死亡率的显著影响。
The United States is facing an unprecedented drug overdose crisis, distinguished from prior epidemics by its severity, widespread impact, and demographic incidence. This study examines demographic overdose trends during the opioid crisis relative to historical disparities. Using a simple decomposition framework, I assess the contributions of specific demographic factors while accounting for other characteristics, finding that many disparities intensify when adjusted for covarying factors. Additionally, I analyze the long-term impacts of OxyContin's launch, discovering that it induced substantial differences in overdose rates by sex and education. While OxyContin contributed to some racial/ethnic disparities, there is evidence that other factors independently shaped these trends. Nonetheless, all demographic groups were substantially impacted by the introduction and promotion of OxyContin. This research highlights how certain groups have been disproportionately affected by the opioid crisis and the foundational role of supply-side shocks to opioid access in explaining the demographics of the overdose death crisis. Supplementary Information: The online version contains supplementary material available at 10.1007/s00148-025-01108-0.